Mark S. Lupone, lifelong resident of Medford, passed away on Thursday, December 3rd. He was 65. Born and raised in Medford, he was the son of the late Americo A. “Mac” and Helen (Albano) Lupone.

Mark loved spending time with his family especially his little sister Julie. He was the best big brother anyone could ask for. Mark had a great smile, which was contagious; he made those around him smile instantly. A fun loving man, he was known to be a jokester, which caused some serious laughing. He was a loving son, the best brother, caring nephew and devoted friend. He will be greatly missed.

Mark was the dear brother of Julie A. Lupone, of Medford. He was the caring nephew of Cathy Albano, of Dracut, and the loving companion of the late Linda Hulitte. He is also survived by many loving cousins from coast to coast.

Mark’s funeral service will be celebrated in the Dello Russo Funeral Home, 306 Main St., Medford, on Sunday, December 13th at 6 PM. Relatives and friends are respectfully invited to attend and may visit with the family from 4 to 6 PM. In lieu of flowers contributions may be made in Mark’s name to the American Diabetes Association, 260 Cochituate Road, Suite 200, Framingham, MA 01701 Or to the National Kidney Foundation, 209 W. Central St., Natick, MA 01760.